I bought a Palmgren 250 a couple decades ago. Used it on my Atlas and currently on my Jet 1340 clone. Yes there are limitations. Working with any metals you have to feed in the correct direction to avoid tool snatching the part and moving things about. I always push away if the tool is below, and pull towards me when the tool is above the part. This way my backlash is removed in the cross slide.
I found that you want the center pivot bolt of the Palmgren for example to be near or even with the spindle centerline. Helps equalize the loading on the vice.
The other day I milled and squared up some aluminum blocks and then cut a slot into both. I was taking 0.01” per pass when cutting the slot with a 3/16” end mill. Unfortunately I didn’t have the right collet so had to use regular chuck. Collet are not really made to hold end mills but can work in a pinch. Usually you would use an end mill holder.
How I mount mine, is on the same stud that the QCTP is held down with. I did make a long spacer to take up the distance, and I make sure that the surfaces are oil free to get the best hold to prevent slipping.
Rules for success
Secure mounting of the vice to slide with no oil between.
Center the vice pivot bolt to spindle center line.
Use end mill tool holder is best.
Conventional milling only.
Tighten the gibs and lock the carriage if possible.
Heavy cuts only in Aluminum
Use power feed on facing cuts
Pierre