I took a look at the handbook on the "maker's" site, it's very similar to the one I use at work as far as the gearing's concerned!
The gearbox isn't a proper quick-change Norton 'box, so you're going to have to swap change-gears whether you stick with inch threads or not... All the knobs do is halve /quarter etc the leadscrew speed, which is why the tpi in the columns on the (inch) chart double as you go down - and why the metric pitches halve!
Taking as an example cutting 24 tpi whe it's alredy set up for 22 tpi: you'll need to swap *both* a and b gears in the gear cover at the headstock end, 56 tooth in the a position and 54 in the b position. That's just step 1...
Once you're good and greasy from swapping change-gears, on to setting the gearbox controls!
you need the top right knob on position 2, lower right on V, other two on B and D, and the left/right-hand feeds/threads lever (lever number 3 up by the speed selection levers) over to the left for normal right-hand threads (daft how they do that - left for right, right for left!) - Despite the words in the book, lever 3 is NOT the spindle direction selector - that's number 15!
Once you have 'em all in position, make sure the feed lever's in its middle (neutral) position, then see if engaging the half-nuts will get the carriage moving (it should!)
Now... chuck a piece of scrap, turn it to a reasonable finish, take the spindle speed down to something sensible (e.g. 70 or 115 RPM, threading's a bit of a timewarp and everything speeds up around you) and engage the half-nuts at one specific number on the thread indicator - remember which number, you'll need it again in a minute!
Take a really light pass just scratching the surface, disengage halfnuts, back the tool out and stop, check the thread against a thread-pitch gauge (there will probably be some in a tap + die set if you dig a bit!) - if all's good, wind the carriage back with the handwheel, set lathe in motion and re-engage the half-nuts when the same number comes around on the indicator, the tool should follow the "scratch" you've already cut.
If this doesn't get you out of the crud, post up some more detail of what you're doing - thread you want to cut, knob positions, what changegears are fitted to the machine etc, and what thread it's actually cutting!
Dave H. (the other one)