I can do it, but it's definitely not ideal. It takes a bit of finesse, and it will never be as good as a machine sharpened end mill. In a tight, sometimes we do what we must. IMO, it's probably not worthwhile. End mills are consumables and unless you have the larger sizes, paying to have them sharpened even professionally can be economically questionable. In the CNC world, you can use regrinds easily, and comp for the oddball size they end up, so some shops do use them, especially carbide or corncob.....even if only on roughout work.