Consider the Tormach TTS tooling system. The advantage is that with multiple ER collets, you don't have to rezero your tooling when removed and reinserted. The system consists of a 3/4" R8 collet and ER chucks with 3/4" shanks. The R8 collet face is modified so that it sits within about .050" from the face of the spindle. When the collet is closed, it draws the collet chuck into close contact with the spindle face in a manner that is accurate and reproducible.
With this system, the ER collet chucks can be preloaded with tooling and tool offsets determined. This can be done off the machine and setting the machine zero only needs be done once. Aside from ER chucks, end mill holder, boring heads, drill chuck adapters, etc. are available. If you want to use R8 collets or tooling it is as simple as pulling the 3/4" collet.
While I haven't heard of it being done, I would expect that it would be possible to adapt to MT3 or MT4 spindles too.
I bought the TTS system when I bought my Tormach mill but I quickly realized the advantages and set my RF30 clone up for it as well.