I have a large vacuum system I use in my wood shop for doing veneer layups and bending.
I make forms with 3/4" MDF ribs on 3" - 4" centers and they are not sufficient for more than a handful of uses.
It is really hard to wrap your brain around how much pressure is exerted at high vacuum. I have had what I though where really solid bullet proof bending forms made from voidless plywood collapse violently under vacuum. It is pretty scary.
I would not consider aluminum at all for the size you are talking about. 24" is just a huge span for a vacuum chamber at the pressures you are talking about. It would be very dangerous if the box collapsed because the aluminum might send off shrapnel as well.
I would weld up a torsion box of 1/2" steel with ribs crossing each other every 4" to 6" depending on the rib height. 4" on center for 3/4" ribs or 6" on center for 1 1/2" ribs. The ribs can go on the outside. Might be able to make the ribs 1/2" and the plates from 3/8" stock. I would just bolt the door on rather than mess around with latches, the door should be at least 1/2" around the edge where the bolts go through or it will deform over time from un-even pressure when bolting up.
Do not forget that the pump will need to run continuously until every last molecule of water is evaporated, and every last bit of trapped gas is exhausted. This can take quite a while with some stuff, and requires a pretty large pump to keep up with the off-gassing that occurs.
Don't waste your time on the systems sold to wood workers. They are seriously over priced and under powered. You want an HVAC pump that is designed to run near continuously, can pull a hard vacuum, and hold that vacuum when turned off with out leaking a bunch of crap back into the chamber (small cheap systems will backflow and fill the chamber with debris). In other words, you need a pump that will cost many hundreds of dollars. These pumps are designed to run for hours at a time while hooked up to an AC system, and are more resistant to corrosive gasses than cheaper pumps.
Do you really need 25" of vacuum? You might want to consider building something that runs a higher pressure and running it for longer. It will probably cut the cost down to a third of building something big. For what it is worth, I have a 15cfm pump on my system. I can do full 4x8 foot veneer layups. I feel my system is underpowered.
Lastly, make sure you double filter the line between the pump and the chamber. I did not filter this line well enough and ruined the seals in my pump and had it leak oil back into a one of a kind pair of matched desktops. It took me two weeks of soaking with ZEP brake cleaner and blotting to get the oil up so I could finish the job. Fortunately I was able to repair the pump.
-Josh